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Literature summary extracted from

  • Caubet, C.; Jonca, N.; Brattsand, M.; Guerrin, M.; Bernard, D.; Schmidt, R.; Egelrud, T.; Simon, M.; Serre, G.
    Degradation of corneodesmosome proteins by two serine proteases of the kallikrein family, SCTE/KLK5/hK5 and SCCE/KLK7/hK7 (2004), J. Invest. Dermatol., 122, 1235-1244.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.4.21.117 kallikrein 5 activates proform of kallikrein 7 Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.21.117 additional information Homo sapiens kallikrein 7 is involved in desquamation ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.B39 Homo sapiens
-
-
-
3.4.21.117 Homo sapiens P49862
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.21.B39 reversed phase chromatography Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.B39 epidermis
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.B39 pro-[stratum corneum chymotryptic enzyme] + H2O stratum corneum tryptic enzyme activates stratum corneum chymotryptic enzyme through cleavage of the 31 kDa proenzyme resulting in the mature 28 kDa enzyme Homo sapiens stratum corneum chymotryptic enzyme + ?
-
 ?
3.4.21.117 corneodesmosin + H2O
-
 Homo sapiens ?
-
 ?
3.4.21.117 desmocollin 1 + H2O
-
 Homo sapiens ?
-
 ?
3.4.21.117 additional information kallikrein 7 is involved in desquamation Homo sapiens ?
-
 ?
3.4.21.117 additional information no cleavage of desmoglein 1 Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.21.B39 hK5
-
 Homo sapiens
3.4.21.B39 KLK5
-
 Homo sapiens
3.4.21.B39 SCTE
-
 Homo sapiens
3.4.21.B39 stratum corneum tryptic enzyme
-
 Homo sapiens
3.4.21.117 hK7
-
 Homo sapiens
3.4.21.117 KLK7
-
 Homo sapiens
3.4.21.117 SCCE
-
 Homo sapiens